REACH Substances of Very High Concern (SVHC) Product Testing

We offer you:

• Product testing for contained *SVHC substances / SVHC screening
• Full SVHC-Analysis
• Product risk based Screening
• REACH SVHC – Compliance
• Project management and study monitoring
• REACH Regulatory Service
• Advice on hazardous substances and management / safety data sheets / MSDS

What can or should you do specifically?

As a manufacturer or importer, we recommend that you ensure compliance with the REACh regulation through complete documentation:

Have your suppliers confirm in writing that their products do not contain any SVHC – substances.

Carefully archive documentation on the materials used, supplier contracts and audit documents as well as analysis reports that have already been carried out for chemical substances.

If you are not sure whether your products contain SVHC – substances, get a chemical analysis done.

Dear customer,

INVITRO-CONNECT GmbH offers you a full range SVHC-service for the testing of your products. The tests are carried out in an accredited test laboratory.

From the development of an excellent test strategy, over the project and laboratory coordination to study monitoring, regulatory expertise and GLP inspections at the affiliated laboratories.
Everything from a single source. Benefit from our wide range of expertise, our experienced collaborators and an international well established network of partners: thoroughly selected experts, toxicologists and more than 80 accredited testing laboratories with an over 20 years’ track record in the industry.

INVITRO-CONNECT GmbH puts together the right team for each project. Thanks to our familiarity with the laboratories and the experts, we commission those most suited for the specific service. That way we can guarantee high-quality results.

We provide final test reports including the registration dossier, of course in the format of your choice, digital as well as on paper and worldwide.

We fully advise and support you with our expertise and the expertise from our whole global in vitro cooperation network.

We offer you all tests and services with the best price-performance ratio.

We are happy to also be your service provider and support your projects reliably – as we already do for many other satisfied clients.
For further information or interest in collaboration with us please do not hesitate to contact us personally. We are pleased to be of service to you.

SVHC Candidate List

With the publication of the first SVHC candidate list on October 28, 2008, many trading companies, importers and manufacturers have the task of determining whether one of these substances is contained in the products / materials sold in a concentration of more than 0.1%. If such a substance is included, then in accordance with Article 33, Paragraph 1, the retail chain must be informed about it if a consumer inquires.

The date of inclusion of a candidate substance on the candidate list is important for the producers and importers of articles who are subject to a reporting obligation for this substance in accordance with Article 7 (2) of the REACH Regulation. According to Article 7 (7), this reporting obligation applies six months after a substance has been added to the candidate list from 01.06.2011.

By 2021, ECHA had added several more substances to the candidate list. There are currently more than 200 SVHC substances.

The identification of substances as substances of very high concern and their inclusion in the candidate list is the first step in the authorization process.

Companies have immediate obligations in relation to the substances on the candidate list.
We carry out the necessary tests for * SVHC substances for you.
Our laboratory test reports are used to document your due diligence towards authorities and your customers.

Of course, we can also have the legal requirements regarding PCP, formaldehyde, chromium (VI), nickel release, etc., as well as further pollutant tests carried out for you, e.g. for allergenic disperse dyes or comprehensive tests according to TOXPROOF®, SG® and other requirement catalogs.

Test samples and material samples can be sent directly to the laboratory for analysis:

INVITRO-CONNECT GmbH
Sample intake SVHC
(the exact laboratory address will be announced after receipt of the order)

*Abbreviation SVHC:
SVHC substances are carcinogenic, mutagenic or toxic to reproduction (CMR, cat. 1 and 2), persistent, bioaccumulative and toxic. Furthermore, there are substances that “according to scientific knowledge are likely to have serious effects on human health or the environment”.
Substances of Very High Concern (SVHC) can be found in mixtures such as paints, inks and glues or in articles such as toys, furniture, textiles and electrical products.

SVHC Candidate List

Substance name expand / collapse	EC No.	CAS No.	Date of inclusion	Reason for inclusion	Decision	IUCLID dataset
Dioctyltin dilaurate, stannane, dioctyl-, bis(coco acyloxy) derivs., and any other stannane, dioctyl-, bis(fatty acyloxy) derivs. wherein C12 is the predominant carbon number of the fatty acyloxy moiety show/hide dioctyltin dilaurate; stannane, dioctyl-, bis(coco acyloxy) derivs. EC No.: – | CAS No.: – Stannane, dioctyl-, bis(coco acyloxy) derivs. EC No.: 293-901-5 | CAS No.: 91648-39-4 Dioctyltin dilaurate EC No.: 222-883-3 | CAS No.: 3648-18-8	–	–	19/01/2021	Toxic for reproduction (Article 57c)	D(2020)9139-DC		Details
Bis(2-(2-methoxyethoxy)ethyl)ether	205-594-7	143-24-8	19/01/2021	Toxic for reproduction (Article 57c)	D(2020)9139-DC		Details
Dibutylbis(pentane-2,4-dionato-O,O’)tin	245-152-0	22673-19-4	25/06/2020	Toxic for reproduction (Article 57c)	D(2020)4578-DC		Details
Butyl 4-hydroxybenzoate	202-318-7	94-26-8	25/06/2020	Endocrine disrupting properties (Article 57(f) – human health)	D(2020)4578-DC		Details
2-methylimidazole	211-765-7	693-98-1	25/06/2020	Toxic for reproduction (Article 57c)	D(2020)4578-DC		Details
1-vinylimidazole	214-012-0	1072-63-5	25/06/2020	Toxic for reproduction (Article 57c)	D(2020)4578-DC		Details
Perfluorobutane sulfonic acid (PFBS) and its salts	–	–	16/01/2020	Equivalent level of concern having probable serious effects to human health (Article 57(f) – human health) Equivalent level of concern having probable serious effects to the environment (Article 57(f) – environment)	ECHA_01_2020.pdf		Details
Diisohexyl phthalate	276-090-2	71850-09-4	16/01/2020	Toxic for reproduction (Article 57c)	ECHA_01_2020.pdf		Details
2-methyl-1-(4-methylthiophenyl)-2-morpholinopropan-1-one	400-600-6	71868-10-5	16/01/2020	Toxic for reproduction (Article 57c)	ECHA_01_2020.pdf		Details
2-benzyl-2-dimethylamino-4′-morpholinobutyrophenone	404-360-3	119313-12-1	16/01/2020	Toxic for reproduction (Article 57c)	ECHA_01_2020.pdf		Details
Tris(4-nonylphenyl, branched and linear) phosphite (TNPP) with ≥ 0.1% w/w of 4-nonylphenol, branched and linear (4-NP) show/hide Phenol, 4-nonyl-, phosphite (3:1) EC No.: – | CAS No.: 3050-88-2 tris(4-nonylphenyl, branched) phosphite EC No.: 701-028-2 | CAS No.: – tris(4-nonylphenyl, branched) phosphite, tris(nonylphenyl) phosphite EC No.: -, 247-759-6 | CAS No.: 26523-78-4 Phenol, p-sec-nonyl-, phosphite EC No.: – | CAS No.: 106599-06-8 Phenol, p-isononyl-, phosphite (3:1) EC No.: – | CAS No.: 31631-13-7	–	–	16/07/2019	Endocrine disrupting properties (Article 57(f) – environment)	ED/71/2019		Details
4-tert-butylphenol	202-679-0	98-54-4	16/07/2019	Endocrine disrupting properties (Article 57(f) – environment)	ED/71/2019 EU/2019/1194		Details
2-methoxyethyl acetate	203-772-9	110-49-6	16/07/2019	Toxic for reproduction (Article 57c)	ED/71/2019		Details
2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propionic acid, its salts and its acyl halides covering any of their individual isomers and combinations thereof show/hide ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoate EC No.: – | CAS No.: 62037-80-3 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propionic acid EC No.: 236-236-8 | CAS No.: 13252-13-6 potassium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propionate EC No.: 266-578-3 | CAS No.: 67118-55-2 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propionyl fluoride EC No.: 218-173-8 | CAS No.: 2062-98-8 Propanoic acid, 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-, (-)- EC No.: – | CAS No.: 75579-40-7 Propanoic acid, 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-, (+)- EC No.: – | CAS No.: 75579-39-4	–	–	16/07/2019	Equivalent level of concern having probable serious effects to human health (Article 57(f) – human health) Equivalent level of concern having probable serious effects to the environment (Article 57(f) – environment)	ED/71/2019		Details
Pyrene	204-927-3	129-00-0	15/01/2019	PBT (Article 57d) vPvB (Article 57e)	ED/88/2018		Details
Phenanthrene	201-581-5	85-01-8	15/01/2019	vPvB (Article 57e)	ED/88/2018		Details
Fluoranthene	205-912-4	206-44-0	15/01/2019	PBT (Article 57d) vPvB (Article 57e)	ED/88/2018		Details
Benzo[k]fluoranthene	205-916-6	207-08-9	15/01/2019	Carcinogenic (Article 57a) PBT (Article 57d) vPvB (Article 57e)	ED/88/2018		Details
2,2-bis(4′-hydroxyphenyl)-4-methylpentane	401-720-1	6807-17-6	15/01/2019	Toxic for reproduction (Article 57c)	ED/88/2018		Details
1,7,7-trimethyl-3-(phenylmethylene)bicyclo[2.2.1]heptan-2-one 3-benzylidene camphor; 3-BC	239-139-9	15087-24-8	15/01/2019	Endocrine disrupting properties (Article 57(f) – environment)	ED/88/2018 EU/2018/2013		Details
Terphenyl, hydrogenated	262-967-7	61788-32-7	27/06/2018	vPvB (Article 57e)	ED/61/2018		Details
Octamethylcyclotetrasiloxane D4	209-136-7	556-67-2	27/06/2018	PBT (Article 57d) vPvB (Article 57e)	ED/61/2018		Details
Lead	231-100-4	7439-92-1	27/06/2018	Toxic for reproduction (Article 57c)	ED/61/2018		Details
Ethylenediamine EDA	203-468-6	107-15-3	27/06/2018	Respiratory sensitising properties (Article 57(f) – human health)	ED/61/2018		Details
Dodecamethylcyclohexasiloxane D6	208-762-8	540-97-6	27/06/2018	PBT (Article 57d) vPvB (Article 57e)	ED/61/2018		Details
Disodium octaborate	234-541-0	12008-41-2	27/06/2018	Toxic for reproduction (Article 57c)	ED/61/2018		Details
Dicyclohexyl phthalate DCHP	201-545-9	84-61-7	27/06/2018	Toxic for reproduction (Article 57c) Endocrine disrupting properties (Article 57(f) – human health)	EU/2018/636 ED/61/2018		Details
Decamethylcyclopentasiloxane D5	208-764-9	541-02-6	27/06/2018	PBT (Article 57d) vPvB (Article 57e)	ED/61/2018		Details
Benzo[ghi]perylene	205-883-8	191-24-2	27/06/2018	PBT (Article 57d) vPvB (Article 57e)	ED/61/2018		Details
Benzene-1,2,4-tricarboxylic acid 1,2 anhydride trimellitic anhydride; TMA	209-008-0	552-30-7	27/06/2018	Respiratory sensitising properties (Article 57(f) – human health)	ED/61/2018 EU/2018/594		Details
Reaction products of 1,3,4-thiadiazolidine-2,5-dithione, formaldehyde and 4-heptylphenol, branched and linear (RP-HP) with ≥0.1% w/w 4-heptylphenol, branched and linear (4-HPbl) show/hide Formaldehyde, reaction products with branched and linear heptylphenol, carbon disulfide and hydrazine EC No.: 300-298-5 | CAS No.: 93925-00-9 Reaction product of 1,3,4-thiadiazolidine-2,5-dithione, formaldehyde and phenol, heptyl derivs. EC No.: 939-460-0 | CAS No.: –	–	–	15/01/2018	Endocrine disrupting properties (Article 57(f) – environment)	ED/01/2018		Details
Chrysene	205-923-4	218-01-9	15/01/2018	Carcinogenic (Article 57a) PBT (Article 57d) vPvB (Article 57e)	ED/01/2018		Details
Cadmium nitrate	233-710-6	10325-94-7	15/01/2018	Carcinogenic (Article 57a) Mutagenic (Article 57b) Specific target organ toxicity after repeated exposure (Article 57(f) – human health)	ED/01/2018		Details
Cadmium hydroxide	244-168-5	21041-95-2	15/01/2018	Carcinogenic (Article 57a) Mutagenic (Article 57b) Specific target organ toxicity after repeated exposure (Article 57(f) – human health)	ED/01/2018		Details
Cadmium carbonate	208-168-9	513-78-0	15/01/2018	Carcinogenic (Article 57a) Mutagenic (Article 57b) Specific target organ toxicity after repeated exposure (Article 57(f) – human health)	ED/01/2018		Details
Benz[a]anthracene	200-280-6	56-55-3	15/01/2018	Carcinogenic (Article 57a) PBT (Article 57d) vPvB (Article 57e)	ED/01/2018		Details
1,6,7,8,9,14,15,16,17,17,18,18-Dodecachloropentacyclo[12.2.1.16,9.02,13.05,10]octadeca-7,15-diene (“Dechlorane Plus”™) covering any of its individual anti- and syn-isomers or any combination thereof show/hide (1S,2S,5R,6R,9S,10S,13R,14R)-1,6,7,8,9,14,15,16,17,17,18,18-Dodecachloropentacyclo[12.2.1.1⁶,⁹.0²,¹³.0⁵,¹⁰]octadeca-7,15-diene EC No.: – | CAS No.: 135821-03-3 (1S,2S,5S,6S,9R,10R,13R,14R)-1,6,7,8,9,14,15,16,17,17,18,18-Dodecachloropentacyclo[12.2.1.1⁶,⁹.0²,¹³.0⁵,¹⁰]octadeca-7,15-diene EC No.: – | CAS No.: 135821-74-8 1,6,7,8,9,14,15,16,17,17,18,18-dodecachloropentacyclo[12.2.1.16,9.02,13.05,10]octadeca-7,15-diene EC No.: 236-948-9 | CAS No.: 13560-89-9 rel-(1R,4S,4aS,6aS,7S,10R,10aR,12aR)-1,2,3,4,7,8,9,10,13,13,14,14-dodecachloro-1,4,4a,5,6,6a,7,10,10a,11,12,12a-dodecahydro-1,4:7,10-dimethanodibenzo[a,e]cyclooctene EC No.: – | CAS No.: – rel-(1R,4S,4aS,6aR,7R,10S,10aS,12aR)-1,2,3,4,7,8,9,10,13,13,14,14-dodecachloro-1,4,4a,5,6,6a,7,10,10a,11,12,12a-dodecahydro-1,4:7,10-dimethanodibenzo[a,e]cyclooctene EC No.: – | CAS No.: –	–	–	15/01/2018	vPvB (Article 57e)	ED/01/2018		Details
Perfluorohexane-1-sulphonic acid and its salts PFHxS show/hide tridecafluorohexanesulphonic acid, compound with 2,2′-iminodiethanol (1:1) EC No.: 274-462-9 | CAS No.: 70225-16-0 potassium perfluorohexane-1-sulphonate EC No.: 223-393-2 | CAS No.: 3871-99-6 perfluorohexane-1-sulphonic acid EC No.: 206-587-1 | CAS No.: 355-46-4 ammonium perfluorohexane-1-sulphonate EC No.: 269-511-6 | CAS No.: 68259-08-5 Sulfonium, [4-[(2-methyl-1-oxo-2-propenyl)oxy]phenyl]diphenyl-, salt with 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-1-hexanesulfonic acid (1:1), polymer with 2-ethyltricyclo[3.3.1.13,7]dec-2-yl 2-methyl-2-propenoate, 3-hydroxytricyclo[3.3.1.13,7]dec-1-yl 2-methyl-2-propenoate and tetrahydro-2-oxo-3-furanyl 2-methyl-2-propenoate EC No.: – | CAS No.: 911027-69-5 1-Hexanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-, cesium salt (1:1) EC No.: – | CAS No.: 92011-17-1 Dibenzo[k,n][1,4,7,10,13]tetraoxathiacyclopentadecinium, 19-[4-(1,1-dimethylethyl)phenyl]-6,7,9,10,12,13-hexahydro-, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-1-hexanesulfonate (1:1) EC No.: – | CAS No.: 928049-42-7 1-Hexanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-, gallium salt (9CI) EC No.: – | CAS No.: 341035-71-0 Sulfonium, bis(4-methylphenyl)phenyl-, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-1-hexanesulfonate (1:1) EC No.: – | CAS No.: 341548-85-4 1-Hexanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-, scandium(3+) salt (3:1) EC No.: – | CAS No.: 350836-93-0 1-Hexanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-, neodymium(3+) salt (3:1) EC No.: – | CAS No.: 41184-65-0 1-Hexanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-, yttrium(3+) salt (3:1) EC No.: – | CAS No.: 41242-12-0 Sulfonium, (thiodi-4,1-phenylene)bis[diphenyl-, salt with 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-1-hexanesulfonic acid (1:2) EC No.: – | CAS No.: 421555-73-9 Iodonium, bis[4-(1,1-dimethylpropyl)phenyl]-, salt with 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-1-hexanesulfonic EC No.: – | CAS No.: 421555-74-0 Sulfonium, tris[4-(1,1-dimethylethyl)phenyl]-, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-1-hexanesulfonate (1:1) EC No.: – | CAS No.: 425670-70-8 Ethanaminium, N-[4-[[4-(diethylamino)phenyl][4-(ethylamino)-1-naphthalenyl]methylene]-2,5-cyclohexadien-1-ylidene]-N-ethyl-, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-1-hexanesulfonate (1:1) EC No.: – | CAS No.: 1310480-24-0 Methanaminium, N-[4-[[4-(dimethylamino)phenyl][4-(ethylamino)-1-naphthalenyl]methylene]-2,5-cyclohexadien-1-ylidene]-N-methyl-, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-1-hexanesulfonate (1:1) EC No.: – | CAS No.: 1310480-27-3 Methanaminium, N-[4-[[4-(dimethylamino)phenyl][4-(phenylamino)-1-naphthalenyl]methylene]-2,5-cyclohexadien-1-ylidene]-N-methyl-, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-1-hexanesulfonate (1:1) EC No.: – | CAS No.: 1310480-28-4 Beta-Cyclodextrin, compd. with 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-1-hexanesulfonic acid ion(1-)(1:1) EC No.: – | CAS No.: 1329995-45-0 Gamma-Cyclodextrin, compd. with 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-1-hexanesulfonic acid ion(1-)(1:1) EC No.: – | CAS No.: 1329995-69-8 Sulfonium, triphenyl-, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-1-hexanesulfonate (1:1) EC No.: – | CAS No.: 144116-10-9 Phosphonium, triphenyl(phenylmethyl)-, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-1-hexanesulfonate (1:1) EC No.: – | CAS No.: 1000597-52-3 1-Butanaminium, N,N,N-tributyl-, salt with 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-1-hexanesulfonic acid EC No.: – | CAS No.: 108427-54-9 Ethanaminium, N,N,N-triethyl-, salt with1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-1-hexanesulfonic acid (1:1) EC No.: – | CAS No.: 108427-55-0 1-Hexanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-, compd. With pyrrolidine (1:1) EC No.: – | CAS No.: 1187817-57-7 Quinolinium, 1-(carboxymethyl)-4-[2-[4-[4-(2,2-diphenylethenyl)phenyl]-1,2,3,3a,4,8b-hexahydrocyclopent[b]indol-7-yl]ethenyl]-, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-1-hexanesulfonate (1:1) EC No.: – | CAS No.: 1462414-59-0 Iodonium, diphenyl-, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-1-hexanesulfonate (1:1) EC No.: – | CAS No.: 153443-35-7 Methanaminium, N,N,N-trimethyl-, salt with 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-1-hexanesulfonic acid (1:1) EC No.: – | CAS No.: 189274-31-5 1-Hexanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-, compd.with 2-methyl-2-propanamine (1:1) EC No.: – | CAS No.: 202189-84-2 Iodonium, bis[4-(1,1-dimethylethyl)phenyl]-, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-1-hexanesulfonate (1:1) EC No.: – | CAS No.: 213740-81-9 1-Hexanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-, lithium salt (1:1) EC No.: – | CAS No.: 55120-77-9 1-Hexanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-, zinc salt EC No.: – | CAS No.: 70136-72-0 Sulfonium, [4-[(2-methyl-1-oxo-2-propen-1-yl)oxy]phenyl]diphenyl-, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-1-hexanesulfonate (1:1) EC No.: – | CAS No.: 911027-68-4 Sulfonium, (4-methylphenyl)diphenyl-, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-1-hexanesulfonate (1:1) EC No.: – | CAS No.: 910606-39-2 Iodonium, bis[(1,1-dimethylethyl)phenyl]-, salt with 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-1-hexanesulfonic acid (1:1) (9CI) EC No.: – | CAS No.: 866621-50-3 1-Hexanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-, compd. with N,N-diethylethanamine (1:1) EC No.: – | CAS No.: 72033-41-1 1-Hexanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-, sodium salt EC No.: – | CAS No.: 82382-12-5	–	–	07/07/2017	vPvB (Article 57e)	ED/30/2017		Details
p-(1,1-dimethylpropyl)phenol	201-280-9	80-46-6	12/01/2017	Endocrine disrupting properties (Article 57(f) – environment)	ED/01/2017		Details
Nonadecafluorodecanoic acid (PFDA) and its sodium and ammonium salts show/hide Decanoic acid, nonadecafluoro-, sodium salt EC No.: – | CAS No.: 3830-45-3 Ammonium nonadecafluorodecanoate EC No.: 221-470-5 | CAS No.: 3108-42-7 Nonadecafluorodecanoic acid EC No.: 206-400-3 | CAS No.: 335-76-2 sodium nonadecafluorodecanoate EC No.: – | CAS No.: 3830-45-3	–	–	12/01/2017	Toxic for reproduction (Article 57c) PBT (Article 57d)	ED/01/2017		Details
4-heptylphenol, branched and linear substances with a linear and/or branched alkyl chain with a carbon number of 7 covalently bound predominantly in position 4 to phenol, covering also UVCB- and well-defined substances which include any of the individual isomers or a combination thereof show/hide 4-heptylphenol EC No.: 217-862-0 | CAS No.: 1987-50-4 Phenol, heptyl derivs. EC No.: 276-743-1 | CAS No.: 72624-02-3 Phenol, 4-(1-ethyl-1,2-dimethylpropyl)- EC No.: – | CAS No.: 30784-27-1 Phenol, 4-(1,1,2,2-tetramethylpropyl)- EC No.: – | CAS No.: 72861-06-4 Phenol, 4-(1,1,3-trimethylbutyl)- EC No.: – | CAS No.: 33104-11-9 Phenol, 4-(1,1-diethylpropyl)- EC No.: – | CAS No.: 37872-24-5 Phenol, 4-(1,1-dimethylpentyl)- EC No.: – | CAS No.: 30784-31-7 Phenol, 4-(1,2,2-trimethylbutyl)- EC No.: – | CAS No.: 911371-06-7 Phenol, 4-(1,2-dimethylpentyl)- EC No.: – | CAS No.: 854904-93-1 Phenol, 4-(1,3,3-trimethylbutyl)- EC No.: – | CAS No.: 911371-07-8 Phenol, 4-(1,3-dimethylpentyl)- EC No.: – | CAS No.: 71945-81-8 Phenol, 4-(1,4-dimethylpentyl)- EC No.: – | CAS No.: 857629-71-1 Phenol, 4-(1-ethyl-2,2-dimethylpropyl)- EC No.: – | CAS No.: 861010-65-3 Phenol, 4-(1-ethyl-3-methylbutyl)- EC No.: – | CAS No.: 854904-92-0 Phenol, 4-(1-ethylpentyl)- EC No.: – | CAS No.: 6465-74-3 Phenol, 4-(1-methylhexyl)- EC No.: – | CAS No.: 6863-24-7 Phenol, 4-(1-propylbutyl)- EC No.: – | CAS No.: 6465-71-0 Phenol, 4-(3-ethylpentyl)- EC No.: – | CAS No.: 911370-98-4 Phenol, 4-(3-methylhexyl)- EC No.: – | CAS No.: 102570-52-5 Phenol, 4-(4-methylhexyl)- EC No.: – | CAS No.: 1139800-98-8 Phenol, 4-(5-methylhexyl)- EC No.: – | CAS No.: 100532-36-3 Phenol, 4-[2-methyl-1-(1-methylethyl)propyl]- EC No.: – | CAS No.: 1824346-00-0 Phenol, 4-tert-heptyl- EC No.: – | CAS No.: 288864-02-8 4-(2,3-dimethylpentan-2-yl)phenol EC No.: 854-135-2 | CAS No.: 861011-60-1 4-(3-methylhexan-3-yl)phenol EC No.: 854-958-7 | CAS No.: 30784-32-8	–	–	12/01/2017	Endocrine disrupting properties (Article 57(f) – environment)	ED/01/2017		Details
4,4′-isopropylidenediphenol Bisphenol A; BPA	201-245-8	80-05-7	12/01/2017	Toxic for reproduction (Article 57c) Endocrine disrupting properties (Article 57(f) – environment) Endocrine disrupting properties (Article 57(f) – human health)	ED/30/2017 ED/01/2017 ED 01/2018		Details
Benzo[def]chrysene (Benzo[a]pyrene)	200-028-5	50-32-8	20/06/2016	Carcinogenic (Article 57a) Mutagenic (Article 57b) Toxic for reproduction (Article 57c) PBT (Article 57d) vPvB (Article 57e)	ED/21/2016		Details
Perfluorononan-1-oic-acid and its sodium and ammonium salts show/hide Ammonium salts of perfluorononan-1-oic-acid EC No.: – | CAS No.: -, 4149-60-4 Perfluorononan-1-oic-acid EC No.: 206-801-3 | CAS No.: 375-95-1 Sodium salts of perfluorononan-1-oic-acid EC No.: – | CAS No.: -, 21049-39-8	–	–	17/12/2015	Toxic for reproduction (Article 57c) PBT (Article 57d)	ED/79/2015		Details
Nitrobenzene	202-716-0	98-95-3	17/12/2015	Toxic for reproduction (Article 57c)	ED/79/2015		Details
2-(2H-benzotriazol-2-yl)-4-(tert-butyl)-6-(sec-butyl)phenol (UV-350)	253-037-1	36437-37-3	17/12/2015	vPvB (Article 57e)	ED/79/2015		Details
2,4-di-tert-butyl-6-(5-chlorobenzotriazol-2-yl)phenol (UV-327)	223-383-8	3864-99-1	17/12/2015	vPvB (Article 57e)	ED/79/2015		Details
1,3-propanesultone	214-317-9	1120-71-4	17/12/2015	Carcinogenic (Article 57a)	ED/79/2015		Details
5-sec-butyl-2-(2,4-dimethylcyclohex-3-en-1-yl)-5-methyl-1,3-dioxane [1], 5-sec-butyl-2-(4,6-dimethylcyclohex-3-en-1-yl)-5-methyl-1,3-dioxane [2] covering any of the individual stereoisomers of [1] and [2] or any combination thereof show/hide Reaction mass of 5-sec-butyl-2-(2,4-dimethylcyclohex-3-en-1-yl)-5-methyl-1,3-dioxane and 5-sec-butyl-2-(4,6-dimethylcyclohex-3-en-1-yl)-5-methyl-1,3-dioxane EC No.: 413-720-9 | CAS No.: 117933-89-8 Reaction mass of 5-[(2R)-butan-2-yl]-2-[(1R,2R)-2,4-dimethylcyclohex-3-en-1-yl]-5-methyl-1,3-dioxane and 5-[(2R)-butan-2-yl]-2-[(1R,2S)-2,4-dimethylcyclohex-3-en-1-yl]-5-methyl-1,3-dioxane and 5-[(2R)-butan-2-yl]-2-[(1S,2R)-2,4-dimethylcyclohex-3-en-1-yl]-5-methyl-1,3-dioxane and 5-[(2R)-butan-2-yl]-2-[(1S,2S)-2,4-dimethylcyclohex-3-en-1-yl]-5-methyl-1,3-dioxane and 5-[(2S)-butan-2-yl]-2-[(1S,2R)-2,4-dimethylcyclohex-3-en-1-yl]-5-methyl-1,3-dioxane and 5-[(2S)-butan-2-yl]-2-[(1S,2S)-2,4-dimethylcyclohex-3-en-1-yl]-5-methyl-1,3-dioxane EC No.: 700-927-7 | CAS No.: – 2-(2,4-Dimethylcyclohex-3-ene-1-yl)-5-methyl-(1-methylpropyl)-1,3-dioxane EC No.: 601-499-3 | CAS No.: 117933-89-8 1,3-Dioxane, 2-[(1R,2R)-2,4-dimethyl-3-cyclohexen-1-yl]-5-methyl-5-(1-methylpropyl)-, trans-rel- EC No.: – | CAS No.: 343934-05-4 1,3-Dioxane, 2-[(1R,2S)-2,4-dimethyl-3-cyclohexen-1-yl]-5-methyl-5-(1-methylpropyl)-, cis- EC No.: – | CAS No.: 676367-04-7 1,3-Dioxane, 2-[(1R,2S)-2,4-dimethyl-3-cyclohexen-1-yl]-5-methyl-5-(1-methylpropyl)-, trans- EC No.: – | CAS No.: 676367-08-1 1,3-Dioxane, 2-[(1S,2R)-2,4-dimethyl-3-cyclohexen-1-yl]-5-methyl-5-(1-methylpropyl)-, cis- EC No.: – | CAS No.: 676367-03-6 1,3-Dioxane, 2-[(1S,2R)-2,4-dimethyl-3-cyclohexen-1-yl]-5-methyl-5-(1-methylpropyl)-, trans- EC No.: – | CAS No.: 676367-07-0 1,3-Dioxane, 2-[(1S,2S)-2,4-dimethyl-3-cyclohexen-1-yl]-5-methyl-5-(1-methylpropyl)-, cis- EC No.: – | CAS No.: 676367-02-5 1,3-Dioxane, 2-[(1S,2S)-2,4-dimethyl-3-cyclohexen-1-yl]-5-methyl-5-(1-methylpropyl)-, trans- EC No.: – | CAS No.: 676367-06-9 5-sec-butyl-2-(2,4-dimethylcyclohex-3-en-1-yl)-5-methyl-1,3-dioxane EC No.: – | CAS No.: – 5-sec-butyl-2-(4,6-dimethylcyclohex-3-en-1-yl)-5-methyl-1,3-dioxane EC No.: – | CAS No.: – 1,3-Dioxane, 2-[(1R,2R)-2,4-dimethyl-3-cyclohexen-1-yl]-5-methyl-5-(1-methylpropyl)-, trans- EC No.: – | CAS No.: 676367-09-2 1,3-Dioxane, 2-[(1R,2R)-2,4-dimethyl-3-cyclohexen-1-yl]-5-methyl-5-(1-methylpropyl)-, cis-rel- EC No.: – | CAS No.: 343934-04-3 1,3-Dioxane, 2-(2,4-dimethyl-3-cyclohexen-1-yl)-5-methyl-5-(1-methylpropyl)- EC No.: – | CAS No.: 186309-28-4 1,3-Dioxane, 2-[(1R,2R)-2,4-dimethyl-3-cyclohexen-1-yl]-5-methyl-5-(1-methylpropyl)-, cis- EC No.: – | CAS No.: 676367-05-8	–	–	15/06/2015	vPvB (Article 57e)	ED/39/2015		Details
1,2-benzenedicarboxylic acid, di-C6-10-alkyl esters or mixed decyl and hexyl and octyl diesters with ≥ 0.3% of dihexyl phthalate (EC No. 201-559-5) show/hide 1,2-Benzenedicarboxylic acid, mixed decyl and hexyl and octyl diesters EC No.: 272-013-1 | CAS No.: 68648-93-1 1,2-Benzenedicarboxylic acid, di-C6-10-alkyl esters EC No.: 271-094-0 | CAS No.: 68515-51-5	–	–	15/06/2015	Toxic for reproduction (Article 57c)	ED/39/2015		Details
Reaction mass of 2-ethylhexyl 10-ethyl-4,4-dioctyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate and 2-ethylhexyl 10-ethyl-4-[[2-[(2-ethylhexyl)oxy]-2-oxoethyl]thio]-4-octyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate (reaction mass of DOTE and MOTE)	–	–	17/12/2014	Toxic for reproduction (Article 57c)	ED/108/2014		Details
Cadmium sulphate	233-331-6	10124-36-4, 31119-53-6	17/12/2014	Carcinogenic (Article 57a) Mutagenic (Article 57b) Toxic for reproduction (Article 57c) Specific target organ toxicity after repeated exposure (Article 57(f) – human health)	ED/108/2014		Details
Cadmium fluoride	232-222-0	7790-79-6	17/12/2014	Carcinogenic (Article 57a) Mutagenic (Article 57b) Toxic for reproduction (Article 57c) Specific target organ toxicity after repeated exposure (Article 57(f) – human health)	ED/108/2014		Details
2-ethylhexyl 10-ethyl-4,4-dioctyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate (DOTE)	239-622-4	15571-58-1	17/12/2014	Toxic for reproduction (Article 57c)	ED/108/2014		Details
2-benzotriazol-2-yl-4,6-di-tert-butylphenol (UV-320)	223-346-6	3846-71-7	17/12/2014	PBT (Article 57d) vPvB (Article 57e)	ED/108/2014		Details
2-(2H-benzotriazol-2-yl)-4,6-ditertpentylphenol (UV-328)	247-384-8	25973-55-1	17/12/2014	PBT (Article 57d) vPvB (Article 57e)	ED/108/2014		Details
Sodium peroxometaborate	231-556-4	7632-04-4	16/06/2014	Toxic for reproduction (Article 57c)	ED/49/2014		Details
Sodium perborate, perboric acid, sodium salt show/hide Perboric acid (H3BO2(O2)), monosodium salt, trihydrate EC No.: 603-902-8 | CAS No.: 13517-20-9 Borate(2-), tetrahydroxybis[μ-(peroxy-κO1:κO2)]di-, sodium (1:2) EC No.: – | CAS No.: 90568-23-3 Sodium perborate EC No.: 239-172-9 | CAS No.: 15120-21-5 Perboric acid, sodium salt EC No.: 234-390-0 | CAS No.: 11138-47-9 Borate(2-), tetrahydroxybis[μ-(peroxy-κO1:κO2)]di-, sodium, hydrate (1:2:6) EC No.: – | CAS No.: 125022-34-6	–	–	16/06/2014	Toxic for reproduction (Article 57c)	ED/49/2014		Details
Cadmium chloride	233-296-7	10108-64-2	16/06/2014	Carcinogenic (Article 57a) Mutagenic (Article 57b) Toxic for reproduction (Article 57c) Specific target organ toxicity after repeated exposure (Article 57(f) – human health)	ED/49/2014		Details
1,2-Benzenedicarboxylic acid, dihexyl ester, branched and linear	271-093-5	68515-50-4	16/06/2014	Toxic for reproduction (Article 57c)	ED/49/2014		Details
Trixylyl phosphate	246-677-8	25155-23-1	16/12/2013	Toxic for reproduction (Article 57c)	ED/121/2013		Details
Lead di(acetate)	206-104-4	301-04-2	16/12/2013	Toxic for reproduction (Article 57c)	ED/121/2013		Details
Imidazolidine-2-thione (2-imidazoline-2-thiol)	202-506-9	96-45-7	16/12/2013	Toxic for reproduction (Article 57c)	ED/121/2013		Details
Disodium 4-amino-3-[[4′-[(2,4-diaminophenyl)azo][1,1′-biphenyl]-4-yl]azo] -5-hydroxy-6-(phenylazo)naphthalene-2,7-disulphonate (C.I. Direct Black 38)	217-710-3	1937-37-7	16/12/2013	Carcinogenic (Article 57a)	ED/121/2013		Details
Disodium 3,3′-[[1,1′-biphenyl]-4,4′-diylbis(azo)]bis(4-aminonaphthalene-1-sulphonate) (C.I. Direct Red 28)	209-358-4	573-58-0	16/12/2013	Carcinogenic (Article 57a)	ED/121/2013		Details
Dihexyl phthalate	201-559-5	84-75-3	16/12/2013	Toxic for reproduction (Article 57c)	ED/121/2013		Details
Cadmium sulphide	215-147-8	1306-23-6	16/12/2013	Carcinogenic (Article 57a) Specific target organ toxicity after repeated exposure (Article 57(f) – human health)	ED/121/2013		Details
Pentadecafluorooctanoic acid (PFOA)	206-397-9	335-67-1	20/06/2013	Toxic for reproduction (Article 57c) PBT (Article 57d)	ED/69/2013		Details
Dipentyl phthalate (DPP)	205-017-9	131-18-0	20/06/2013	Toxic for reproduction (Article 57c)	ED/69/2013		Details
Cadmium oxide	215-146-2	1306-19-0	20/06/2013	Carcinogenic (Article 57a) Specific target organ toxicity after repeated exposure (Article 57(f) – human health)	ED/69/2013		Details
Cadmium	231-152-8	7440-43-9	20/06/2013	Carcinogenic (Article 57a) Specific target organ toxicity after repeated exposure (Article 57(f) – human health)	ED/69/2013		Details
Ammonium pentadecafluorooctanoate (APFO)	223-320-4	3825-26-1	20/06/2013	Toxic for reproduction (Article 57c) PBT (Article 57d)	ED/69/2013		Details
4-Nonylphenol, branched and linear, ethoxylated substances with a linear and/or branched alkyl chain with a carbon number of 9 covalently bound in position 4 to phenol, ethoxylated covering UVCB- and well-defined substances, polymers and homologues, which include any of the individual isomers and/or combinations thereof show/hide Nonylphenol, ethoxylated (8-EO) (9016-45-9) EC No.: 931-754-7 | CAS No.: – Nonylphenol, ethoxylated (6,5-EO) (9016-45-9) EC No.: 931-753-1 | CAS No.: – Nonylphenol, ethoxylated EC No.: 500-024-6 | CAS No.: 9016-45-9 2-[2-(4-nonylphenoxy)ethoxy]ethanol EC No.: 243-816-4 | CAS No.: 20427-84-3 20-(4-nonylphenoxy)-3,6,9,12,15,18-hexaoxaicosan-1-ol EC No.: 248-743-1 | CAS No.: 27942-27-4 Nonylphenol, ethoxylated (10-EO) (9016-45-9) EC No.: 931-755-2 | CAS No.: – 2-[2-[2-[2-(4-nonylphenoxy)ethoxy]ethoxy]ethoxy]ethanol EC No.: 230-770-5 | CAS No.: 7311-27-5 Nonylphenol, branched, ethoxylated (CAS# 68412-54-4) EC No.: 932-688-1 | CAS No.: – Nonylphenol, branched, ethoxylated 1 – 2.5 moles ethoxylated EC No.: 500-209-1 | CAS No.: 68412-54-4 4-Nonylphenol, ethoxylated 1 – 2.5 moles ethoxylated EC No.: 500-045-0 | CAS No.: 26027-38-3 Nonylphenol, ethoxylated (15-EO) (9016-45-9) EC No.: 931-756-8 | CAS No.: – 26-(4-Nonylphenoxy)-3,6,9,12,15,18,21,24- octaoxahexacosan -1-ol EC No.: – | CAS No.: 14409-72-4 2-{2-[4-(3,6-dimethylheptan-3-yl)phenoxy]ethoxy}ethanol EC No.: 687-833-9 | CAS No.: 1119449-38-5 Nonylphenol, ethoxylated (polymer) EC No.: 938-618-6 | CAS No.: – Nonylphenol, ethoxylated (EO = 4) EC No.: 939-975-0 | CAS No.: – Nonylphenol, ethoxylated (EO = 10) EC No.: 939-993-9 | CAS No.: – 4-t-Nonylphenol-diethoxylate EC No.: – | CAS No.: 156609-10-8 2-[4-(3,6-dimethylheptan-3-yl)phenoxy]ethanol EC No.: 687-832-3 | CAS No.: 1119449-37-4 Nonylphenolpolyglycolether EC No.: 932-998-7 | CAS No.: – Poly (oxy-1,2-ethanediyl), alpha -(nonylphenyl)-omega-hydroxy-, branched (CAS# 68412-54-4) EC No.: 932-337-2 | CAS No.: 68412-54-4 4-Nonylphenol, branched, ethoxylated (CAS: 127087-87-0) EC No.: 932-098-4 | CAS No.: 127087-87-0 3,6,9,12-Tetraoxatetradecan-1-ol, 14-(4-nonylphenoxy)- EC No.: – | CAS No.: 20636-48-0 Isononylphenol, ethoxylated EC No.: 609-346-2 | CAS No.: 37205-87-1 p-Nonylphenol hexaethoxylate EC No.: – | CAS No.: 34166-38-6 4-Nonylphenol, branched, ethoxylated 1 – 2.5 moles ethoxylated EC No.: 500-315-8 | CAS No.: 127087-87-0 Ethanol, 2-(4-nonylphenoxy)- EC No.: – | CAS No.: 104-35-8 23-(nonylphenoxy)-3,6,9,12,15,18,21-heptaoxatricosan-1-ol EC No.: 248-293-6 | CAS No.: 27177-05-5 26-(nonylphenoxy)-3,6,9,12,15,18,21,24-octaoxahexacosan-1-ol EC No.: 247-816-5 | CAS No.: 26571-11-9 14-(nonylphenoxy)-3,6,9,12-tetraoxatetradecan-1-ol EC No.: 247-555-7 | CAS No.: 26264-02-8 Poly(oxy-1,2-ethanediyl), a-(nonylphenyl)-w-hydroxy- (CAS 9016-45-9) EC No.: 931-562-3 | CAS No.: 9016-45-9	–	–	20/06/2013	Endocrine disrupting properties (Article 57(f) – environment)	ED/69/2013		Details
Trilead dioxide phosphonate	235-252-2	12141-20-7	19/12/2012	Toxic for reproduction (Article 57c)	ED/169/2012		Details
Trilead bis(carbonate) dihydroxide	215-290-6	1319-46-6	19/12/2012	Toxic for reproduction (Article 57c)	ED/169/2012		Details
Tricosafluorododecanoic acid	206-203-2	307-55-1	19/12/2012	vPvB (Article 57e)	ED/169/2012		Details
Tetralead trioxide sulphate	235-380-9	12202-17-4	19/12/2012	Toxic for reproduction (Article 57c)	ED/169/2012